Neuro Basis of Autism

This course examines the neurobiological processes underlying autism spectrum disorders. In this seminar course, we will first examine the brain phenotypes associated with Autism Spectrum Disorders (ASD), in addition to investigating the genetic and environmental contributions to the etiology and pathophysiology of ASD. After an initial examination of the clinical literature and research, we will focus on animal models of ASD, including those of syndromic causes of autism (Rett Syndrome, Tuberous Sclerosis, Fragile X) and investigate changes in neurotransmitter systems and synaptic dysfunctions in the brain of these models.